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New Research on Male Pattern Baldness
July 29, 2009: 0 comment(s)
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Given a choice most men would rather keep their hair than lose it. In 2007 men spent $115 million dollars on hair transplant and global revenues for baldness treatment recently pushed over $405 million dollars annually. Research at McGill University, King’s College London and GlaxoSmithKline, Inc. has reveals how newly discovered baldness genes put 1 out of 7 men at risk hair loss.
80% of men who are bald are believed to lose their hair due to hereditary factors. Researches have known for years that genes on the female X chromosome were a factor in male pattern baldness. Male pattern baldness is the most common form of baldness and results in the M pattern of hair loss seen in men where hair recedes in the frontal hairline and over the back of the head. New findings have shown that additional genes play a dominant role in the development of baldness.
Dr. Brent Richards of McGill University explained that the idea of male baldness resulting from genes on the mother’s side of the family is only part of the story. “It’s been long recognized that there must be several genes causing male pattern baldness. Until now, no one could identify those other genes. If you have both the risk variants we discovered on chromosome 20 and the unrelated known variant on the X chromosome, your risk of becoming bald increases sevenfold”.
“What is startling is that one in seven men have both of those risk variants. That’s 14% of the population!”
The study looked at 1,125 men with male pattern baldness and their genome. A genome is all of the hereditary information found in the genes that make up human chromosomes. This resulted in the discovery of two previously unknown genetic variations on chromosome 20 that dramatically increased the risk for male pattern baldness. The finding was then confirmed in an additional 1650 men.
“We’ve only identified a cause,” reported Richards. “Treating male pattern baldness will require more research. But, of course, the first step in finding a way to treat most conditions is to first identify the cause.”
Dr. Tim Spector also of King’s College added, “Early prediction before hair loss starts may lead to some interesting therapies that are more effective than treating late stage hair loss.”
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